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17 janvier 2022
- doi: 10.4000/bmsap.8987
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info:eu-repo/semantics/reference/issn/0037-8984
Ce document est lié à :
info:eu-repo/semantics/reference/issn/1777-5469
https://creativecommons.org/licenses/by-nc-nd/4.0/ , info:eu-repo/semantics/openAccess
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Diseases and hygiene People Man Humanity (Human beings) Human race Mankind Homo sapiens Humankind Humans Sickness Human beings--Diseases Morbidity Illness Sicknesses IllnessesCiter ce document
López Gfeller Brina et al., « Rise and fall of deleterious variants: the origins of modern genetic diseases », Bulletins et mémoires de la société d’anthropologie de Paris, ID : 10.4000/bmsap.8987
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For two decades, sequencing genomes has significantly helped to identify genetic causes of diseases observed in modern humans, leading to the emergence of genetic medicine. This raises questions about the presence of deleterious variants, and consequently diseases, in ancient humans too, as well as when and where these variants first appeared during human evolution. As the Neolithic transition brought a major change in diet and life style in Western Eurasia, we examined the health status of p...