Syndrome des ovaires polykystiques chez l’adolescente diabétique ou obèse [Polycystic ovary syndrome in obese or type 1 diabetic (T1D) adolescent girls]
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14 octobre 2020
- doi: 10.53738/REVMED.2020.16.710.1941
- issn: 1660-9379
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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_60A93331D71E3
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T. Bouthors et al., « Syndrome des ovaires polykystiques chez l’adolescente diabétique ou obèse [Polycystic ovary syndrome in obese or type 1 diabetic (T1D) adolescent girls] », Serveur académique Lausannois, ID : 10.53738/REVMED.2020.16.710.1941
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Polycystic ovary syndrome (PCOS) is frequent during adolescence (prevalence ≈ 6 %), and the prevalence increases in obese or type 1 diabetic (T1D) adolescent girls. During puberty, PCOS diagnosis is difficult because of the overlap with some pubertal physiologic signs. The 2017 international consortium suggests two required diagnostic criteria: persistent menstrual disturbances and hyperandrogenism. PCOS physiopathology is complex, including interactions between genetic, epigenetic factors, primary ovarian abnormalities, neuroendocrine alterations, hormonal and metabolic factors. Insulin seems to have a central place in obese or T1D adolescent girls. The treatment is still debated and should be monitored according to the main symptoms.