14 juin 2023
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G.R. Joliat et al., « Nouveautés dans la prise en charge de l’échinococcose alvéolaire [Novelties on the management of alveolar echinococcosis] », Serveur académique Lausannois, ID : 10.53738/REVMED.2023.19.831.1192
Alveolar echinococcosis is an endemic parasitosis in Switzerland. This pathology mainly infects the liver and develops similarly as a malignant tumor with its ability to spread into the hepatic parenchyma and its capacity of developing distant lesions via hematogenous dissemination. Treatment is based on complete surgical resection coupled with albendazole treatment. Recently, ex vivo liver resections with auto-transplantation have been shown to be feasible in case of end-stage alveolar echinococcosis. Moreover, new biomarkers such as programmed death-ligand 1 (PD-L1), a protein with immunomodulation property, have shown their potential impact on the treatment and follow-up of patients with alveolar echinococcosis.