Apical size and deltaA expression predict adult neural stem cell decisions along lineage progression
Fiche du document
9 janvier 2023
- doi: 10.57745/K4IPF2
Mots-clés
Medicine, Health and Life Sciences neural stem cells Multiphoton Fluorescence Microscopy NotchSujets proches
Expressive behaviorCiter ce document
Nicolas DRAY et al., « Apical size and deltaA expression predict adult neural stem cell decisions along lineage progression », Recherche Data Gouv, ID : 10.57745/K4IPF2
Métriques
Partage / Export
Résumé
Codes, tabular data and some raw data used in the publication: Apical size and deltaA expression predict adult neural stem cell decisions along lineage progression, Mancini L. et al. 2022. bioRxiv 2022. We use long-term intravital imaging of NSCs in the zebrafish adult telencephalon to link activation and division mode with predictive cellular and molecular parameters. We reveal that apical surface area and expression of the Notch ligand DeltaA predict NSC activation frequency, while deltaA expression marks NSC commitment to neurogenesis.