Fiche du document
mars 2017
- handle: 10670/1.3g9urn
- hal: hal-02190911
- doi: 10.1016/j.neubiorev.2017.01.020
- PUBMEDCENTRAL: PMC5303129
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1016/j.neubiorev.2017.01.020
Sujets proches
Tsʻeu Tzʻu Ci Tse Cerebrum Mind Ageing Senescence Age--Physiological effect Older persons Older adults Seniors (Older people) Elderly people Old people Senior citizens Aging people AgedCiter ce document
Qu Tian et al., « The brain map of gait variability in aging, cognitive impairment and dementia—A systematic review », HALSHS : archive ouverte en Sciences de l’Homme et de la Société, ID : 10.1016/j.neubiorev.2017.01.020
Métriques
Partage / Export
Résumé
While gait variability may reflect subtle changes due to aging or cognitive impairment (CI), associated brain characteristics remain unclear. We summarize structural and functional neuroimaging findings associated with gait variability in older adults with and without CI and dementia.We identified 17 eligible studies; all were cross-sectional; few examined multiple brain areas. In older adults, temporal gait variability was associated with structural differences in medial areas important for lower limb coordination and balance. Both temporal and spatial gait variability were associated with structural and functional differences in hippocampus and primary sensorimotor cortex and structural differences in anterior cingulate cortex, basal ganglia, association tracts, and posterior thalamic radiation. In CI or dementia, some associations were found in primary motor cortex, hippocampus, prefrontal cortex and basal ganglia.In older adults, gait variability may be associated with areas important for sensorimotor integration and coordination. To comprehend the neural basis of gait variability with aging and CI, longitudinal studies of multiple brain areas are needed.