Improvement in quality of life and sexual function in patients affected by vulvar lichen sclerosus treated with combined autologous platelet-rich plasma and fat grafting
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2023
- ISIDORE Id: 10670/1.439dd2...
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lichen sclerosus sexual function lipofilling quality of life fat grafting autologous platelet-rich plasmaSujets proches
Life, Quality ofCiter ce document
Francesco Casabona et al., « Improvement in quality of life and sexual function in patients affected by vulvar lichen sclerosus treated with combined autologous platelet-rich plasma and fat grafting », European Journal of Dermatology, ID : 10670/1.439dd2...
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Background: Vulvar lichen sclerosus (LS) severely impairs patients’ quality of life. Objectives: To evaluate the impact of a combined application of autologous platelet-rich plasma (PRP) and fat grafting as treatment for vulvar LS on patient quality of life. Materials & Methods: We reviewed the clinical charts of 72 patients affected by LS, who underwent regenerative surgery. The patients’ quality of life was assessed using: the Dermatology Life Quality Index (DLQI), the Skindex-29, the Female Sexual Function Index (FSFI) and the patient-administered - Clinical Scoring System (CSS). Results: After reconstructive surgery, all scores improved: Skindex-29 (-31.8 [IQR: 42.1, -21.8] points; ppppppConclusion: Combined treatment with PRP and fat grafting proved to be effective in improving the quality of life of patients with vulvar LS.
