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2023
- ISIDORE Id: 10670/1.447dc3...
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eccrine carcinoma hidradenoma hidradenocarcinoma sweat gland neoplasms Cutaneous adnexal neoplasmsSujets proches
Tumor spread Spread of cancer Dissemination of cancer Tumor metastasis Tumor dissemination Metastatic cancer Metastases Cancer--Dissemination Neoplasm metastasis Cancer metastasis Cancer--MetastasisCiter ce document
Patrícia Amoedo et al., « Metastatic hidradenocarcinoma: a report of two rare cases », European Journal of Dermatology, ID : 10670/1.447dc3...
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Background: Hidradenocarcinoma is a rare malignant sweat gland tumour, characterized by a slow but aggressive course, with high rates of local recurrence and metastasis. Due to its rarity, histological criteria and therapeutic guidelines are poorly defined, posing a major challenge for clinicians and pathologists. Objectives: To present two new cases of metastatic hidradenocarcinoma as well as a review of the literature. Materials & Methods: We describe two case studies and a review of the literature based on a search using the MEDLINE (PubMed) electronic database. Results: The first patient was a 61-year-old woman with a perimamillary hidradenocarcinoma that arose from the malignant transformation of a benign childhood lesion and developed regional lymph node metastases after wide excision and adjuvant radiotherapy. The second patient was a 63-year-old man who developed cutaneous and renal metastases several years after the complete excision of a lumbar hidradenocarcinoma. As far as we can ascertain, kidney metastasis from hidradenocarcinoma has not previously been described. Conclusion: Most authors recommend wide excision as the treatment of choice for hidradenocarcinoma, however, optimal adjuvant therapy remains to be determined. Our cases add to the limited knowledge available, but high-quality studies to find new effective treatments are needed.
