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- handle: 10670/1.82e8lf
- hal: hal-01482661
- doi: 10.1093/schbul/sbv099
- PUBMEDCENTRAL: PMC4681554
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info:eu-repo/semantics/altIdentifier/doi/10.1093/schbul/sbv099
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Quality of Life -bio]/Santé publique et épidémiologie -bio]/Human health and pathology/Psychiatrics and mental healthSujets proches
Schizophrenic disorders Dementia praecoxCiter ce document
Fabrice Berna et al., « A Meta-Analysis of Autobiographical Memory Studies in Schizophrenia ă Spectrum Disorder », HAL-SHS : économie et finance, ID : 10.1093/schbul/sbv099
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Meta-analyses and reviews on cognitive disorders in schizophrenia have ă shown that the most robust and common cognitive deficits are found in ă episodic memory and executive functions. More complex memory domains, ă such as autobiographical memory (AM), are also impaired in ă schizophrenia, but such impairments are reported less often despite ă their negative impact on patients' outcome. In contrast to episodic ă memory, assessed in laboratory tasks, memories of past personal events ă are much more complex and directly relate to the self. The meta-analysis ă included 20 studies, 571 patients with schizophrenia spectrum disorder, ă and 503 comparison subjects. It found moderate-to-large effect sizes ă with regard to the 3 parameters commonly used to assess AM: memory ă specificity (g = -0.97), richness of detail (g = -1.40), and conscious ă recollection (g = -0.62). These effect sizes were in the same range as ă those found in other memory domains in schizophrenia; for this reason, ă we propose that defective memories of personal past events should be ă regarded as a major cognitive impairment in this illness.