Current status of persistent chronic hyperkalemia in France: An expert consensus using the Delphi method
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2022
- ISIDORE Id: 10670/1.94142b...
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Patrick Rossignol et al., « Current status of persistent chronic hyperkalemia in France: An expert consensus using the Delphi method », Néphrologie & Thérapeutique, ID : 10670/1.94142b...
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IntroductionIn France, no consensus document on the management of persistent hyperkalemia is currently available. Variability in clinical practices has been observed.MethodsA consensus statement on the definition and management of persistent hyperkalemia was developed by a Delphi panel of French nephrologists between December 2019 (26 voting participants among 40 invited panelists in the first round) and June 2020 (20 voting participants among 26 panelists in the second round).ResultsPersistent hyperkalemia not controlled with current treatment strategies can be defined as the occurrence of two or more hyperkalemia episodes within a year despite administration of cation-exchange resins or loop diuretics during the same year. Certain patient characteristics (diabetes, chronic kidney disease from stage 3B to stage 5 without dialysis, and chronic heart failure) are associated with an increased risk of developing persistent hyperkalemia. There is a medical need for the management of persistent hyperkalemia in patients treated with renin-angiotensin-aldosterone system inhibitors that is not met by current treatment strategies (including available cation-exchange resins).ConclusionsThe panel expressed a need for new treatment strategies validated by clinical trials.
