Effects of cognitive impairment on prosodic parameters of speech production planning in Multiple Sclerosis
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2019
- handle: 10670/1.98e8xl
- halshs: halshs-01529435
- doi: 10.1111/jnp.12127
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info:eu-repo/semantics/altIdentifier/doi/10.1111/jnp.12127
info:eu-repo/semantics/OpenAccess
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Céline Delooze et al., « Effects of cognitive impairment on prosodic parameters of speech production planning in Multiple Sclerosis », HAL-SHS : linguistique, ID : 10.1111/jnp.12127
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Résumé
Cognitive impairment (CI) affects 40–65% of patients with multiple sclerosis (MS). CI canhave a negative impact on a patient’s everyday activities, such as engaging in conversations.Speech production planning ability is crucial for successful verbal interactions and thus forpreserving social and occupational skills. This study investigates the effect of cognitivelinguisticdemand and CI on speech production planning in MS, as reflected in speechprosody. A secondary aim is to explore the clinical potential of prosodic features for theprediction of an individual’s cognitive status in MS. A total of 45 subjects, that is 22 healthycontrols (HC) and 23 patients in early stages of relapsing-remitting MS, underwentneuropsychological tests probing specific cognitive processes involved in speechproduction planning. All subjects also performed a read speech task, in which they hadto read isolated sentences manipulated as for phonological length. Results show that thespeech of MS patients with CI is mainly affected at the temporal level (articulation andspeech rate, pause duration). Regression analyses further indicate that rate measures arecorrelated with working memory scores. In addition, linear discriminant analysis showsthe ROC AUC of identifying MS patients with CI is 0.70 (95% confidence interval: 0.68–0.73). Our findings indicate that prosodic planning is deficient in patients with MS-CI andthat the scope of planning depends on patients’ cognitive abilities. We discuss howspeech-based approaches could be used as an ecological method for the assessment andmonitoring of CI in MS.