Relação entre o Nível Sérico Basal de GH e de IGF-1 e a Autonomia e o Estado de Condicionamento Físico da Idosa Ativa

Résumé 0

"The activity of the GH/IGF-1 axis declines significantly with aging, which may result in compromised functional autonomy and state of physic fitness. We measured basal serum levels of GH and IGF-1 in twenty elderly women (mean age 68.0 ± 4.9 years) undergoing weight training in order to determine the possible correlations with performance of activities of daily living (ADLs) and state of physical fitness, using components of body composition, strength, flexibility, localized muscle resistance and aerobic capacity. The basal levels of GH and IGF-1 were close to the expected values for this age group (1.4 ± 1.12 ng/mL; 141.5 ± 79.0 ng/mL). There were no statistically significant correlations of GH and IGF-1 with functional autonomy (p=0,29; 0,24). Similarly, there were no significant correlations of either IGF-1 with components of physical fitness. The only significant negative correlation observedwas for GH and IMC (r=-0.52, p=0.02). In conclusion, the mechanisms that change the % fat associated to the aging even are¿nt totally understood, the reduction of the secretion of the GH can have impact about this process, despite normal basal levels GH e IGF-1 in active elderly women, this study did not show an association among these values and measures of autonomy for ADLS and state of physical fitness."