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23 septembre 2021
- handle: 10670/1.a2f7ko
- hal: hal-03386389
- doi: 10.1371/journal.ppat.1009892
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info:eu-repo/semantics/altIdentifier/doi/10.1371/journal.ppat.1009892
Ce document est lié à :
info:eu-repo/grantAgreement//637647/EU/Immunity, DEvelopment and Microbiota: Understanding the Continuous Construction of Biological Identity/IDEM
info:eu-repo/semantics/OpenAccess
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-bio] -bio]/Cancer -bio]/ImmunologySujets proches
Natural science Sciences Science of scienceCiter ce document
Hannah Kaminski et al., « Immunological exhaustion: How to make a disparate concept operational? », HAL-SHS : histoire, philosophie et sociologie des sciences et des techniques, ID : 10.1371/journal.ppat.1009892
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In this essay, we show that 3 distinct approaches to immunological exhaustion coexist and that they only partially overlap, generating potential misunderstandings. Exploring cases ranging from viral infections to cancer, we propose that it is crucial, for experimental and therapeutic purposes, to clarify these approaches and their interconnections so as to make the concept of exhaustion genuinely operational.