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30 juin 2020
- ISIDORE Id: 10670/1.bd97d9...
- hal: hal-04336270
- doi: 10.3233/JAD-200017
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info:eu-repo/semantics/altIdentifier/doi/10.3233/JAD-200017
info:eu-repo/semantics/OpenAccess
Mots-clés
Alzheimer’s disease, apathy, awareness, depression Alzheimer's disease Apathy Awareness DepressionSujets proches
Impassivity Indifference Unconcern illnessCiter ce document
Jean-Pierre Jacus et al., « Modelling Awareness in Alzheimer’s Disease », HAL SHS (Sciences de l’Homme et de la Société), ID : 10.3233/JAD-200017
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Résumé
. This study aimed to provide a model of awareness in Alzheimer’s disease using the stage of the disease as a risk factor. Awareness was assessed using three methods (patient-caregiver discrepancy, prediction-performance discrepancy, clinical rating). Twenty-five healthy control subjects and sixty-one patients participated, with measures of cognition, apathy, depression, and awareness. These measures were introduced into a manual backward regression. Confounding factors impacting at least 15% of the exposure factor estimate were maintained in the model. Except for the prediction performance discrepancy, also presenting cognitive associations, the other awareness assessments suggested a major role of depressionand apathy as impacting factors.
