The combined influence of Attention Deficit Hyperactivity Disorder and childhood trauma on the Substance Use Disorder severity
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4 septembre 2024
- ISIDORE Id: 10670/1.d41661...
- hal: hal-04707195
info:eu-repo/semantics/OpenAccess
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Thibault Hennequin et al., « The combined influence of Attention Deficit Hyperactivity Disorder and childhood trauma on the Substance Use Disorder severity », HAL SHS (Sciences de l’Homme et de la Société), ID : 10670/1.d41661...
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Context: Attention Deficit Hyperactivity Disorder (ADHD) and childhood trauma (CT) are identified in 23% and up to 63% of patients suffering from substance use disorder (SUD), compared with 2.5% and 28%, in the general population, respectively. A growing body of evidence suggests a negative impact of both CT and ADHD on SUD, including an increased severity of the SUD. Yet, the combined influence of CT and ADHD on SUD remains poorly understood. Notably, the type and number of CT could elicit different effects on SUDs in ADHD patients.Objective: To investigate the frequency of combined ADHD and CT in treatment-seeking SUD outpatients and to characterize their combined influence on the severity of SUDs.Methods: outpatients seeking treatment for SUD were consecutively recruited and evaluated for the main SUD diagnosis and severity (number of criteria) using the MINI-S SUD module. ADHD was assessed using the MINI-S ADHD module. CT was assessed using the Childhood Trauma Questionnaire (CTQ), allowing us to consider five trauma types and their cumulative number. In the whole sample and in ADHD vs. non-ADHD patients, we compared the number of DSM5 criteria of the main SUD according to the presence vs. absence of any CT, of each CT type, and as a function of the total number of CT types. We performed Kruskal-Wallis tests, considering statistical significance at p
