Awareness, apathy, and depression in Alzheimer's disease and mild cognitive impairment

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6 mars 2017

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HAL SHS (Sciences de l’Homme et de la Société)

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Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1002/brb3.661

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Archives ouvertes

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Centre pour la communication scientifique directe

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info:eu-repo/semantics/OpenAccess

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Alzheimer’s disease apathy awareness depression mild cognitive impairment

Sujets proches En

Impassivity Indifference Unconcern

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Jean-Pierre Jacus, « Awareness, apathy, and depression in Alzheimer's disease and mild cognitive impairment », HAL SHS (Sciences de l’Homme et de la Société), ID : 10.1002/brb3.661

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Introduction Results from studies on awareness disorders in Alzheimer's disease ( AD ) are controversial because the methodologies, the “objects” of awareness, and the patients' pathologic stage all vary. Our study aimed to compare scores and correlates of awareness according to the stage of the disease and the assessment method. Methods We compared 20 mild AD patients to 20 mild cognitive impairment ( MCI ) patients, using the Patient Competency Rating Scale ( PCRS ; patient vs. caregiver report) and the Self‐Consciousness Scale (rating scale). All patients underwent cognitive, psycho‐affective and behavioral assessments (global cognition, executive functions, episodic memory, anxiety‐depression, and apathy measures). Results Groups were matched for age, education, and gender. They were comparable on the depression, anxiety, apathy and awareness scales ( p s > .05), and differed for all cognitive variables ( p

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