Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle
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Date
25 avril 2013
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- handle: 10670/1.fjy2tg
- doi: 10.1023/A:1020741226752
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Ammonia Ammoniac Anastomose portocave chirurgicale Encéphalopathie hépatique Expression des gènes Foie Gene expression Glutamine synthetase Hepatic encephalopathy Liver Muscles squelettiques Portacaval anastomosis Skeletal muscleSujets proches
Muscle Musculature Myodynamics MyologyCiter ce document
Paul Desjardins et al., « Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle », Papyrus : le dépôt institutionnel de l'Université de Montréal, ID : 10.1023/A:1020741226752
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The effects of chronic liver insufficiency resulting from end-to-side portacaval anastomosis (PCA) on glutamine synthetase (GS) activities, protein and gene expression were studied in brain, liver and skeletal muscle of male adult rats. Four weeks following PCA, activities of GS in cerebral cortex and cerebellum were reduced by 32\% and 37\% (p