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14 février 2020
- handle: 10670/1.oljvqo
- hal: hal-03237108
- doi: 10.1136/gutjnl-2019-320027
- PUBMED: 31907297
- SCIENCESPO: 2441/5jurhvsnvf8osrv97hqcdssa59
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info:eu-repo/semantics/altIdentifier/doi/10.1136/gutjnl-2019-320027
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pmid/31907297
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/hdl/2441/5jurhvsnvf8osrv97hqcdssa59
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Tsʻeu Tzʻu Ci Tse Infectious diseasesCiter ce document
Camille Besombes et al., « The epidemiology of hepatitis delta virus infection in Cameroon », Archive ouverte de Sciences Po (SPIRE), ID : 10.1136/gutjnl-2019-320027
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Objective To investigate the distribution and risk factors of hepatitis delta virus (HDV) infection in Cameroon. Design We tested for hepatitis B virus (HBV) surface antigen (HBsAg) and anti-HDV antibody 14 150 samples collected during a survey whose participants were representative of the Cameroonian adult population. The samples had already been tested for hepatitis C virus and HIV antibodies. Results Overall, 1621/14 150 (weighted prevalence=11.9%) participants were HBsAg positive, among whom 224/1621 (10.6%) were anti-HDV positive. In 2011, the estimated numbers of HBsAg positive and HDV seropositives were 1 160 799 and 122 910 in the 15–49 years age group, respectively. There were substantial regional variations in prevalence of chronic HBV infection, but even more so for HDV (from 1% to 54%). In multivariable analysis, HDV seropositivity was independently associated with living with an HDV-seropositive person (OR=8.80; 95% CI: 3.23 to 24.0), being HIV infected (OR=2.82; 95% CI: 1.32 to 6.02) and living in the South (latitude