2005
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Salud Pública de México
Juan Germán Celis-Quintal et al., « Clinical profile of dengue hemorrhagic fever cases in Mexico », Salud Pública de México, ID : 10670/1.p9zup6
"Objective. Dengue hemorrhagic fever is a public healthproblem in Mexico since 1994. With four serotypes circulatingthe risk of epidemic dengue hemorrhagic fever is increasing.Material and Methods. We describe the clinicalfeatures of confirmed cases in the social security health system(IMSS) from 1995 to 2003. Clinical picture and epidemiologicalfeatures were compared and a multivariate modelwas fitted to evaluate associations. Results. Cases weredivided into two groups: 438 patients with dengue fever,including 109 cases with hemorrhagic manifestations withoutthrombocytopenia, and 977 cases with dengue hemorrhagicfever, including 79 deaths. The main risk factorsassociated with mortality were hematemesis (RR 2.6; CI 95%1.4-4.6) and melena (RR 2.2; CI 95% 1.2-3.7). Conclusions.Our results characterize the clinical profile of dengue hemorrhagicfever cases in Mexico and identify prognostic factorsto alert clinician for the prevention of a fatal evolution."