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25 avril 2013
- handle: 10670/1.ry1f3y
- doi: 10.1023/B:MEBR.0000043971.72170.a2
Mots-clés
Acute liver failure Défaillance hépatique aigüe Encéphalopathie hépatique Hepatic encephalopathy Hypothermia Hypothermie Intracranial pressure Liver transplantation Pression intracrânienne Transplantation hépatiqueSujets proches
Hepatic failure Failure of the liver Hepatic insufficiency Liver failureCiter ce document
Rajiv Jalan et al., « Hypothermia in acute liver failure », Papyrus : le dépôt institutionnel de l'Université de Montréal, ID : 10.1023/B:MEBR.0000043971.72170.a2
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Résumé
The development of encephalopathy in patients with acute liver injury defines the occurrence of liver failure. The encephalopathy of acute liver failure is characterized by brain edema which manifests clinically as increased intracranial pressure. Despite the best available medical therapies a significant proportion of patients with acute liver failure die due to brain herniation. The present review explores the experimental and clinical data to define the role of hypothermia as a treatment modality for increased intracranial pressure in patients with acute liver failure.