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1 juin 2016
- handle: 10670/1.slow7t
Ce document est lié à :
10.15174/au.2016.937
info:eu-repo/semantics/openAccess
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Julio Montes-Ávila et al., « Antioxidant activity and antimicrobial evaluation of 1-benzyl-1,2,3-triazole », Acta universitaria, ID : 10670/1.slow7t
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: This paper reports biological activities of 1-benzyl-1,2,3-triazoles: antimicrobial by broth microdilution method, antioxidant by DPPH (2,2-diphenyl-1-picrylhydrazyl)• inactivation assay and toxicity by brine shrimp (Artemia salina) assay. The compound 1-(1-Benzyl-1H-1,2,3-triazol-4-yl) cyclopentanol (50 µg/mL to 200 µg/mL) presented selective moderate inhibition of Staphylococcus aureus 3 growth whereas the same effect of 3-(1-Benzyl-1H-1,2,3-triazol-4-yl)propan-1-ol was registered against Escherichia coli AO11, E. coli AO15 and Salmonella enterica serovar Typhi. 5g-i compounds showed the highest DPPH• scanvenging. Synthetic 1,2,3-triazole evaluated compounds were classified in the range moderately toxic to non-toxic. Thus, based in the previously/actually published information, they could be a source of compounds with biological activities of importance for human health.