Clinical markers associated with acute laboratory-confirmed Dengue infection: results of a national epidemiological surveillance system
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2017
- handle: 10670/1.wdd8ua
- 0124-0064
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Revista de Salud Pública
Mots-clés
Salud case NLM) Dengue epidemiology communicable diseasesSujets proches
Dengue fever Breakbone feverCiter ce document
Efrén Murillo-Zamora et al., « Clinical markers associated with acute laboratory-confirmed Dengue infection: results of a national epidemiological surveillance system », Revista de Salud Pública, ID : 10670/1.wdd8ua
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Résumé
"Objective To evaluate the association of several clinical markers with acute labora - tory-positive Dengue Virus infection. Methods A hospital-based case-control study was conducted in the state of Colima, Mexico, by using information from the National System of Epidemiological Survei - llance (Sistema Nacional de Vigilancia Epidemiológica [SINAVE]) for Dengue. Data from 2 732 cases and 2 775 frequency-matched controls were analyzed. Odds Ratio (OR) and the 95 % Confidence Interval (CI), estimated by means of logistic regres - sion models, were used. Results The presence of skin rash (OR=1,7; 95 % CI 1,5–2,1), persisting vomiting (OR=1,8; 95 % CI 1,5–2,3) and increased capillary fragility (petechiae, ecchymosis, hematoma or positive tourniquet test; OR=1,8; 95 % CI 1,2–2,6) were associated with laboratory-positive infection. Conclusions Three clinical markers were significantly associated with an increased risk of acute laboratory-confirmed dengue infection. These findings would support accurate and timely diagnosis of dengue in laboratory-limited settings."