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1 septembre 2010
- handle: 10670/1.x4vffq
info:eu-repo/semantics/openAccess
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chitosan fibrin gelatin hyaluronic acid scaffoldSujets proches
Hyaluronan GelatineCiter ce document
Javier Enrione et al., « Characterization of a Gelatin/Chitosan/Hyaluronan scaffold-polymer », Electronic Journal of Biotechnology, ID : 10670/1.x4vffq
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Gelatin, chitosan and hyaluronic acid are natural components used to prepare polymeric scaffold in tissue engineering. The physical properties of these materials confer an appropriate microenvironment for cells, which can be used as a regeneration system for skin and cartilage. In this work, we prepared and characterized a Gelatin/Chitosan/Hyaluronan lyophilized-polymer. Physical properties of lyophilized-polymer changed slightly with moisture, but when polymer was totally hydrated the elasticity changed significantly. Thermophysical characterisation indicated that temperatures higher than 30ºC could modify irreversibly the polymeric matrix probably due to protein denaturation. Besides, we used the polymer as scaffold to prepare a biosynthetic-skin, reporting biological behaviour and its mechanical properties.