Quantitative estimation of optical properties in bilayer media within the subdiffusive regime using tilted fiber-optic probe diffuse reflectance spectroscopy, part 2: probe design, realization, and experimental validation
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- 20.500.11794/163343
- 1083-3668
- doi: 10.1117/1.JBO.29.10.105002
- 39474361
http://purl.org/coar/access_right/c_abf2
Mots-clés
Diffuse reflectance Bilayer Subdiffusive Intrinsic optical properties Fiber optic probe Monte Carlo simulation Peau -- Physiologie Spectroscopie de réflectance Optique des fibres Méthode de Monte-CarloSujets proches
Integument (Skin) Cutis Reflection spectroscopy Coefficient of reflection Total reflectance, Radiant Radiant total reflectance Reflectivity (Optics) Reflection coefficient Reflection factor Property--Law and legislation FibresCiter ce document
Philippe De Tillieux et al., « Quantitative estimation of optical properties in bilayer media within the subdiffusive regime using tilted fiber-optic probe diffuse reflectance spectroscopy, part 2: probe design, realization, and experimental validation », CorpusUL, l'archive ouverte de l'université Laval, ID : 10.1117/1.JBO.29.10.105002
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Résumé
Significance: Tissues like skin have a layered structure where each layer's optical properties vary significantly. However, traditional diffuse reflectance spectroscopy assumes a homogeneous medium, often leading to estimations that reflects the properties of neither layer. There's a clear need for probes that can precisely measure the optical properties of layered tissues. Aim: This paper aims to design a diffuse reflectance probe capable of accurately estimating the optical properties of bilayer tissues in the subdiffusive regime. Approach: Using Monte Carlo simulations, we evaluated key geometric factors— fiber placement, tilt angle, diameter, and numerical aperture—on optical property estimation, following the methodology in Part I. A robust design is proposed that balances accurate intrinsic optical property (IOP) calculations with practical experimental constraints. Results: The designed probe, featuring eight illumination and eight detection fibers with varying spacings and tilt angles. The estimation error of the IOP calculation for bilayer phantoms is less than 20% for top layers with thicknesses between 0.2 and 1.0 mm. Conclusion: Building on the approach from Part I and using a precise calibration, the probe effectively quantified and distinguished the IOPs of bilayer samples, particularly those relevant to early skin pathology detection and characterization.
