N. Déglon

Discipline

Psychologie (8) Histoire, Philosophie et Sociologie des sciences (5) Sciences de l'information et de la communication (1)

Type de document

Articles (57) Recensions (4) Livres et chapitres d'ouvrages (2)

Co-auteur

Date

Source

Mot-clé

Mice (31) protéine (29) Brain (28) cerveau (28) maladie (27) Expression (27) maladie (27) gène (25) Animals (24) Treatment (23) Neurons (23) mutant (21) Human beings (21) Huntington's disease (21) Example (19) Development (18) Cells (18) modèle (17) Astrocytes (17) vecteur (14) Central nervous system (14) Models (14) spectacle (13) Rats (13) Nervous system--Degeneration (13) Proteins (12) puits (11) thérapie (11) pathologie (11) adulte (11)

Documents écrit par N. Déglon (59) | parle de N. Déglon (0)

Gene editing as a therapeutic strategy for spinocerebellar ataxia type-3.
N. Déglon
Mono- and Biallelic Inactivation of Huntingtin Gene in Patient-Specific Induced Pluripotent Stem Cells Reveal HTT Roles in Striatal Development and Neuronal Functions.
M. Louessard et al. (2024)
Limitations of Dual-Single Guide RNA CRISPR Strategies for the Treatment of Central Nervous System Genetic Disorders.
F. Duarte et al.
Semi-automated workflows to quantify AAV transduction in various brain areas and predict gene editing outcome for neurological disorders.
F. Duarte et al. (8 juin 2023)
Disruption of Astrocyte-Dependent Dopamine Control in the Developing Medial Prefrontal Cortex Leads to Excessive Grooming in Mice.
F. Petrelli et al. (1 juin 2023)
Tau promotes oxidative stress-associated cycling neurons in S phase as a pro-survival mechanism: Possible implication for Alzheimer's disease.
M. Denechaud et al.
Tau Transfer via Extracellular Vesicles Disturbs the Astrocytic Mitochondrial System.
R. Perbet et al. (23 mars 2023)
Revisiting the outcome of adult wild-type Htt inactivation in the context of HTT-lowering strategies for Huntington's disease.
S. Regio et al. (2023)
Central Nervous System Gene Therapy: Present Developments and Emerging Trends Accelerating Industry-Academia Pathways.
M. Rybarikova et al.
Thrombolysis by PLAT/tPA increases serum free IGF1 leading to a decrease of deleterious autophagy following brain ischemia.
A.M. Thiebaut et al.
Correction: Maximizing lentiviral vector gene transfer in the CNS.
M. Humbel et al.
Extracellular vesicles: Major actors of heterogeneity in tau spreading among human tauopathies.
E. Leroux et al. (2 févr. 2022)
Lactate transporters in the rat barrel cortex sustain whisker-dependent BOLD fMRI signal and behavioral performance.
H. Roumes et al. (23 nov. 2021)
Maximizing lentiviral vector gene transfer in the CNS.
M. Humbel et al.
Corrigendum: Genome Editing for CNS Disorders.
F. Duarte et al. (2021)
Glucose metabolism links astroglial mitochondria to cannabinoid effects.
R. Serrat et al. (23 juil. 2020)
Lentiviral mediated RPE65 gene transfer in healthy hiPSCs-derived retinal pigment epithelial cells markedly increased RPE65 mRNA, but modestly protein level.
F. Udry et al. (1 juin 2020)
Dysfunction of homeostatic control of dopamine by astrocytes in the developing prefrontal cortex leads to cognitive impairments.
F. Petrelli et al.
Genome Editing for CNS Disorders.
F. Duarte et al. (2020)
Efficacy of THN201, a Combination of Donepezil and Mefloquine, to Reverse Neurocognitive Deficits in Alzheimer's Disease.
M. Droguerre et al. (2020)
A New Tool for In Vivo Study of Astrocyte Connexin 43 in Brain.
M. Droguerre et al. (4 déc. 2019)
Scalable Production of AAV Vectors in Orbitally Shaken HEK293 Cells.
D. Blessing et al. (14 juin 2019)
Cell-Type-Specific Gene Expression Profiling in Adult Mouse Brain Reveals Normal and Disease-State Signatures.
N. Merienne et al. (26 févr. 2019)
Development of Efficient AAV2/DJ-Based Viral Vectors to Selectively Downregulate the Expression of Neuronal or Astrocytic Target Proteins in the Rat Central Nervous System.
C. Jollé et al. (2019)
Different tau species lead to heterogeneous tau pathology propagation and misfolding.
S. Dujardin et al. (29 nov. 2018)

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