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- doi: 10.1007/s00428-020-02892-8
- issn: 0945-6317
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info:eu-repo/semantics/altIdentifier/doi/10.1007/s00428-020-02892-8
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info:eu-repo/semantics/altIdentifier/pmid/32696224
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info:eu-repo/semantics/altIdentifier/eissn/1432-2307
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info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_54935FA3A9BF1
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Bowel diseases Intestinal diseases Enteropathy Gall-bladderCiter ce document
J.L. Dargent et al., « Lymph node involvement by enteropathy-like indolent NK-cell proliferation. », Serveur académique Lausannois, ID : 10.1007/s00428-020-02892-8
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Natural killer (NK)-cell enteropathy (NKCE) and lymphomatoid gastropathy (LG) are closely related lymphoproliferative disorders (LPDs) composed of mature and Epstein-Barr virus (EBV)-negative NK-cells. Although these uncommon and indolent lymphoid proliferations mostly arise within the gastrointestinal (GI) tract as their designations implies, a few cases have been reported outside the GI tract. We hereby describe a unique case of lymph node infiltration by such EBV-negative NK-cell proliferation fortuitously found during routine examination of a gallbladder resected for biliary lithiasis. The histologic, phenotypic, and molecular features of this NK-cell proliferation, which were very similar if not identical to those previously reported in NKCE or LG, suggest that similar indolent EBV-negative NK-cell LPDs may also occasionally involve lymph nodes.