Fiche du document
2008
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/doi/10.1186/gb-2008-9-12-r168
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pmid/19055709
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/pissn/1465-6914[electronic]
Ce document est lié à :
info:eu-repo/semantics/altIdentifier/urn/urn:nbn:ch:serval-BIB_6836FD75BA2C1
info:eu-repo/semantics/openAccess , Copying allowed only for non-profit organizations , https://serval.unil.ch/disclaimer
Sujets proches
Units of inheritance Units of heredityCiter ce document
C. Attanasio et al., « Assaying the regulatory potential of mammalian conserved non-coding sequences in human cells. », Serveur académique Lausannois, ID : 10.1186/gb-2008-9-12-r168
Métriques
Partage / Export
Résumé
BACKGROUND: Conserved non-coding sequences in the human genome are approximately tenfold more abundant than known genes, and have been hypothesized to mark the locations of cis-regulatory elements. However, the global contribution of conserved non-coding sequences to the transcriptional regulation of human genes is currently unknown. Deeply conserved elements shared between humans and teleost fish predominantly flank genes active during morphogenesis and are enriched for positive transcriptional regulatory elements. However, such deeply conserved elements account for