Fiche du document
2021
- handle: 10670/1.g7qwkj
Cairn
Mots-clés
surgery Rolandic area compound muscle action potentials intraoperative neurophysiological monitoring new permanent motor deficitSujets proches
Diseases--Surgery Surgery, PrimitiveCiter ce document
Shuang Wang et al., « Surgical treatment of children with drug-resistant epilepsy involving the Rolandic area », Epileptic Disorders, ID : 10670/1.g7qwkj
Métriques
Partage / Export
Résumé
ObjectiveWe retrospectively analysed the clinical features and prognostic factors of surgery in children with drug-resistant epilepsy involving the Rolandic area, and the relationship between the stable compound muscle action potentials (CMAPs) of intraoperative neurophysiological monitoring (IONM) and good motor function outcomes postoperatively.MethodsA study was conducted on the clinical data of 91 patients with epilepsy who underwent epilepsy surgery involving the Rolandic area and IONM from November 2015 to February 2019.ResultsIn total, 91 patients were included in this study. The median age at seizure onset was 1.3 years old. The median age at surgery was 4.4 years old. Twenty-seven patients (29.7%), with age at onset below three years old, had epileptic spasms. The central operculum was the most common surgical region in 52 patients (57.1%). The most common pathology was focal cortical dysplasia (FCD) in 67 patients. At the last follow-up visit, 69 patients (75.8%) were seizure-free. Interictal epileptiform discharges in the Rolandic area were associated with good seizure outcome (p=0.016). Out of 91 patients, successful IONM was performed in 88 patients (96.7%). Stable CMAP was seen in 79 of 88 patients (89.8%), and irreversible disappearance of CMAP was seen in nine patients (10.2%). New permanent motor deficit was observed in 13 of 88 patients (14.8%). There was a significant correlation between stable CMAP and good motor function outcome (p